As smugglers attempt to sneak drugs across the Caribbean, U.S. law enforcement agencies work to intercept the shipments before they reach land.
Across cities and farms, meth addiction grips the state of Indiana, overwhelming cops and forcing countless residents to seek "refuge in oblivion."
In America's Motor City, dealers cut corners to sell molly to the masses while police officers try to "think like the bad guys."
On the rough streets of Oakland, law enforcement searches for a mysterious RV rumored to be driven by a high-profile drug distributor.
Addicts, dealers and law enforcement officials speak about Baltimore's transformation into "the heroin capital of America."
South of the border, drug traffickers use every trick in the book to push mass amounts of marijuana into the United States.