Kirsten is recruited into a covert government agency to be 'stitched' into the minds of the recently deceased, using their memories to investigate murders and decipher mysteries that otherwise would have gone to the grave. Working alongside Kirsten is Cameron, a brilliant neuroscientist whose passion for the program is evident in his work. The secret program is headed by Maggie, a skilled veteran of covert operations, and includes Linus, a socially immature bioelectrical engineer and communications technician. Kirsten's roommate, Camille, a gifted computer science grad student, is also recruited to use her skills to assist Kirsten in her new role as a 'stitcher.'
A dangerous new drug has claimed the life of a young woman and, while the Stitchers team is looking for its source, they run into Detective Fisher, who is on the same trail.
When a murky stitch doesn’t give enough evidence against a newlywed husband accused of killing his wife, Kirsten attempts to prove her strong feelings about his guilt. This effect on Kirsten, brought about by residual emotion from the stitch, makes Cameron worry that she will end up like Marta. Meanwhile, Linus and Camille get to know each other better.
When Cameron's neighbor is killed, the Stitchers group works to determine if the bullet was really meant for Cameron. As they stakeout the location from Cameron's apartment, Kirsten finds that she enjoys the reconnaissance, maybe a little too much. Meanwhile, Cameron shares more details with Kirsten about Marta's disastrous stitch.
When the algorithm for the Stitchers program turns up among thousands of classified documents hidden by a conspiracy theorist, Kirsten starts to suspect her colleagues. Meanwhile, Kirsten starts getting cryptic messages from an unexpected source.
The Stitchers team investigates a mysterious car accident that resulted in the death of a traumatic brain injury researcher. Meanwhile, Kirsten asks Linus for help deciphering a clue left by Ed Clark as she continues to question Maggie for more information on the origin of the Stitchers program.
Kirsten surprises the Stitchers team when they discover that she has a boyfriend, Liam, who shows up suddenly, prompting Maggie to covertly gather information on him. Meanwhile, a young woman's extravagant social life may be the clue to her death.
It’s Kirsten’s birthday and the Stitchers team is assigned to look into a disease researcher’s suicide. When the body begins showing signs that it is carrying a deadly virus, the whole lab is placed under quarantine. The team jumps to action as they search for a way out, racing against the clock as, one-by-one, they come down with symptoms of exposure.
The Stitchers team investigates the murder of an online psychic whose symbolic, layered memories are further complicated when Kristen sees the murder of another person in the stitch. Maggie expresses her reservations about Kirsten’s relationship with Liam. Meanwhile, Camille hesitantly agrees to meet Linus’s parents.
The Stitchers team is on the defence when Cameron and Detective Fisher are targeted in a shooting. Kirsten's stitch leads them to Robert Barbiero, a security expert who has worked with Maggie in the past and was close to Kirsten's mom. As Kirsten follows the clues that Ed Clark left her, she finds unexpected answers to long-held questions.
While Camille preps for her annual Halloween bash, the Stitchers team investigates the suicide of a young man, who may have abducted a missing college student. The stitch leaves Kirsten spooked, and she begins to worry she's being haunted by him as they race to find the missing girl.
Highly intelligent and emotionally distant, Kirsten Clark has an aptitude for technology but never expected that she’d be hacking into the minds of the recently deceased.
Kirsten Clark’s life lays in the balance as the Stitchers team works to bounce her back into the real world after she became trapped in a stitch attempting to find her mother. Fueled by his love for Kirsten, Cameron finds a way to bring her back to reality, but it could cost them their relationship. Meanwhile, the Stitchers lab is on lockdown, leaving an anxious Linus unable to check on his father’s condition after surgery. But, as the team prepares to be reassigned for breaking protocol, NSA Director Mitchell Blair surprises everyone by demanding an emergency stitch that yields shocking new information.
The Stitchers team investigates the case of a young woman found dead in her wealthy boyfriend’s pool. Meanwhile, Linus feels a connection to Ivy, Cameron has growing concern for Kirsten’s emotional vulnerability and Camille is intrigued by an attractive medical examiner who likes to meet in unusual places.
A high-profile divorce attorney is murdered and the Stitchers team must sort through a plethora of suspects. Meanwhile, Linus discovers the cause of the neurosync issues in the stitches, which directly affects Kirsten and Cameron.
When an MI6 agent is found dead, Kirsten struggles to sort through his memories due to the visual codes that the spy used to keep secrets. Meanwhile, Linus and Camille go on a double date, but not with each other.
Cameron’s estranged father, currently serving time in prison for white-collar crimes, is accused of murdering a prison guard. Going against protocol, Kirsten stitches into the guard’s memory for clues.
After an engineer ends up dead, his colleague and work rival becomes a suspect. However, upon examining some stitches, Kirsten and the team uncover that he was a part of an underground gaming club. The team must juggle saving a falling satellite while Cameron takes a walk on the wild side when he infiltrates the gaming ring to get close to another suspect.
When Kirsten wakes up to find that everyone in the stitch lab, except Cameron, is missing, the two search everywhere but only find a series of mysterious clues. Eventually Kirsten realizes that she's still stitched into an autistic man with unique empathetic abilities. Kirsten is forced to confront her own emotions about her relationship with Cameron and unlock a memory in the victim's mind to bounce back
The Stitchers team investigates the murder of an ex-Air Force officer who is found murdered by what seems like a UFO, and the trail leads to a former co-worker and renowned UFO expert. The memories in the stitch have the team wondering if UFOs and extraterrestrial beings really exist.
A series of murders, including a professional volleyball player, lead the Stitchers team searching the darkest corners of the Internet. Meanwhile, Kirsten gives Maggie an ultimatum.
When a hacker is found dead, the team learns he blackmailed an Ashley Madison-like website and threatened to release their client list online
When Fisher's mentor turns up dead, Kirsten's stitch reveals the officer was murdered by a serial killer she's been chasing for years. The Stitchers team picks up the detective's leads in an effort to finally bring the suspect to justice, but danger arrives in an unexpected form when Cameron is trapped with the killer. Camille's rebellious older brother Theo arrives in town with a whole lot of trouble. Meanwhile, Cameron is finally honest with Kirsten about his feelings for her.
When an unidentified, severely damaged body is recovered in a dumpster, Kirsten’s stitch divulges that the victim has two death scenes from two very different times in his life. When it’s clear the victim had valuable information that could put a lot of people in danger, the team’s investigation leads them to Dr. Naomi Burke, a physicist with a hidden agenda. Camille tires of her brother Theo’s irresponsible ways and finally puts her foot down. Meanwhile, Linus turns to Cameron for help with a sticky situation and Detective Fisher and Kirsten uncover a clue about her father.
When a young woman falls to her death with a cryptic note attached to her body, Kirsten is convinced the message is somehow tied to her own past. But when the stitch reveals the victim was brainwashed to kill movie director Roman Bain, the team ends up in a race against time to find the person responsible before someone gets seriously hurt. Meanwhile, Camille’s defense training unexpectedly reunites her with Liam
After a Chinese pop star is murdered, her bodyguard Mei Ling is accused of negligence in letting the crime happen. But when Kirsten stitches in, she realizes the bodyguard was poisoned before the singer died. The team now has to race against the clock to find the murderer before Mei Ling is sent back to China to face charges. Kirsten has to answer questions from her friends about her obsession with finding Daniel Stinger, but finally makes progress on her search. Meanwhile, Cameron is nervous when Kirsten tells him she wants to meet Nina, and Camille continues to cross paths with Liam.
When a bright, young lawyer is found dead, the team suspects she was murdered because of a case she was working on. After theorizing the lawyer was killed because she discovered something criminal about her firm's high profile client, the team heads to the firm to interview her four ambitious coworkers, each of whom seems more suspicious than the last. While at the firm, Maggie crosses paths with a former college boyfriend (guest star Dondre Whitfield, "Mistresses") who may be closer to the murder than she'd like to admit. Meanwhile, Camille's interactions with Liam take a surprising turn, and Kirsten learns something shocking during the stitch.
The Stitchers team goes into overdrive when a plane lands in Los Angeles with multiple dead passengers and no apparent cause. Now racing against the clock to determine if this is a terrorist attack or the work of a fellow passenger, Kirsten is tasked with stitching into one victim after another to learn exactly what happened. Cameron worries about Kirsten's well-being and their new dynamic in light of his relationship with Nina. Meanwhile, Camille tries to help Linus through a personal issue, and Liam continues to cause problems.
Mitchell Blair directs Kirsten to shut down all investigation into finding her father. But Kirsten has finally made contact with someone she thinks can lead her to him. To gain her source's trust, she tries to explain her role in the Stitchers program, without actually revealing the program's nature. Treading carefully, Kirsten recounts the team's current case, in which a series of murders is tied to a wildly popular new app.
Kirsten is angered by Liam’s treachery, but before she can find her father to seek answers, he disappears. She searches for information, but gets more than she bargained for when she discovers a shocking family secret. Now Kirsten finds herself heading down a dark and dangerous path into her own memories to seek the truth – at any cost.